Medical nanofiber membranes

ChitoFib 

Bioactive nanofibrous structures of ChitoFib with chitosan can be enriched by gelatine into ChitoFib G, a product that adheres to various types of absorbent materials and structures (nonwovens, microfibre structures, PUR foams, etc.). 

A combination of ChitoFib / ChitoFib G with bioactive layer on absorbent materials brings a totally new opportunity for innovation and improvement of wound dressing products. It combines biologically active gelling layers promoting cell proliferation in newly formed skin tissue and the benefits of absorbent materials extending time intervals between dressings.

Nano Medical offers the production of ChitoFib (pure chitosan) and ChitoFib G (chitosan / gelatine blend) nanofiber structures for wound dressing and surgical applications. The materials are suitable for uncontaminated wounds.

Both variants can be enriched with an antimicrobial agent (chlorhexidine or nanosilver) to cover contaminated wounds.

Nanofiber layer based on chitosan can also be widely used for dry skin masks in cosmetic industry as skin regeneration. Other active substances carried inside the nanofiber layer open vast variety of skin mask treatment.   

The unique patented technology of chitosan-based nanofiber layers production

Chitosan-based gelling nanofiber technology ChitoFib

Chitosan/gelatine-based gelling nanofiber technology ChitoFib G

  • The unique technology of chitosan-based nanofiber layers ChitoFib uses the bioactive natural material chitosan of plant (vegetal) origin.
  • Biodegradable nanofibrous structures at a mass per unit area of ​​1.0 – 20.0 grams/m2
  • Enriched with antimicrobial additive (silver, chlorhexidine)
  • Applicable to various types of nonwovens or foam absorbent for use in medical devices (wound covers)
  • Self-supporting nanofibrous layers in the weight of 5 and more grams/m2

Bioactive nanofibrous structures ChitoFib / ChitoFib G apply to various types of absorbent materials and structures (nonwovens, microfibre structures, PUR foams). Affixing the nanofibrous structure to the surface of the absorbent material does not reduce its absorptive capacity.

  

The combination of ChitoFib / ChitoFib G bioactive layer on absorbent materials brings a new quality to wound healing materials. It combines biologically active gelling layers promoting cell proliferation in newly formed skin tissue and the benefits of absorbent materials extending time intervals between dressings.

Benefit of utilization of nanofibrous layers Chitofib / Chitofib G

  • Creates a gel when in contact with fluids (using wet healing in wound applications, does not dry the wound), minimizes pain when applied to wounds
  • Accelerates wound healing and tissue regeneration due to nanostructure in combination with biopolymers 
  • Prevents microbial infection from the external environment due to the nanostructure of the layer (nanostructure prevents the penetration of bacteria) and the natural effect of chitosan (antimicrobial effect)
  • Limits maceration - no lateral wicking 
  • Versatility - different layer thicknesses applicable to different absorbent layers make it possible to design unique materials for wound healing
  • Suitable for all types of wounds - surgical, traumatic, chronic, burns, diabetic feet and bedsores
  • Can be used as carriers of bioactive substances (antimicrobial and pharmacologically active substances) with the possibility to control their release 
  • Sterilizable by 25 kGy gamma radiation

Applications and use

  • Medical devices – patches, wound covers, surgical material
  • Cosmetics – materials for skin regeneration after cosmetic procedures
  • Pharmaceuticals, food supplements – carriers of pharmacologically active substances for transdermal or oral administration
Nano Medical is introducing the world’s first industrial production of chitosan-based nanofiber layers according to GMP for application in medical devices.

Nano Medical Service

  • Custom production of the nanofibrous layer according to Nano Medical patented technology ChitoFib/ChitoFib G
  • Lamination of the nanofibrous layer with other textile materials and carriers
  • Custom production of plasters and wound cover
  • Custom material and product development of nanofibrous materials for applications in medical devices, pharmacy